In many ways, the scientific method is the foundation of everything science has discovered and accomplished. The scientific method represents a methodical and useful tool for asking questions and seeking answers. Although it is the responsibility of researchers to adhere to the scientific method, it is also possible to evaluate scientific results and reconstruct how the scientific method was used in experiments. In this article, the scientific method will be traced in an experiment involving mice and coffee, where researchers were interested in the effect that drinking coffee had on mice genetically engineered to become diabetic. The scientific method follows a predictable pattern of asking questions, testing those questions, and then drawing conclusions from the tests conducted. Any research begins with a question, which is the basis of the scientific method. From there, you need to conduct research to determine what tests have already been performed regarding the selected question. This helps scientists avoid repeating tests unnecessarily and can help target their tests. Using the information gathered, researchers can then build a hypothesis. A hypothesis is a statement about what is expected to happen. An experiment is then designed to test the hypothesis. During the experiment, it is important to keep as many factors identical as possible, except for the one factor that is being tested. After the experiment, all results should be analyzed to decide whether the hypothesis was correct, incorrect, or somewhere in between. In this experiment, reported in the Journal of Agricultural and Food Chemistry (Yamauchi et al, 2010), the researchers researched the experiment... at the center of the article... the experiment of Yamauchi and his fellow researchers represents a typical application of the scientific method in biological research. The scientific method was carefully followed and only a small conflict of interest appeared to concern the validity of the study. The research findings are also important, as they could have a significant impact on a disease whose incidence is increasing and shows no signs of slowing. Overall, this experiment is an excellent example of good research, which follows the scientific method and builds on the research of other scientists. Works cited Yamauchi et al. (2010). Coffee and caffeine improve hyperglycemia, fatty liver, and inflammatory adipocytokine expression in spontaneously diabetic KK-Ay mice. Journal of Agricultural and Food Chemistry, 58(9), 5597-5603. May 12 PMID: 20405946, ISSN: 1520-5118.