Introduction• In the natural environment, where many organisms exist, competition arises to survive and use resources, bacteria begin their fight by using chemical weapons to kill other microorganisms or simply inhibit their growth (Cannibalism: asocial behavior in sporulation) (Cannibalism and fratricide) (Production of the cannibalism toxin SDP), the effect of these chemicals begins with its broad effect as an antimicrobial substance on unrelated bacterial species, to a very specific bacteriocin , peptides that affect closely related strains, without forgetting to improve the producer's immunity against its own toxins in all members of the population, (Cannibalism: asocial behavior of sporulation (Cannibalism and fratricide), a new relationship within the population of the same species including the production of a sister killing toxins which we will talk about in our review as mechanisms known as cannibalism, a mechanism discovered in the gram-positive species of Bacillus subtilis acts to kill identical or semi-identical sister cells, brothers, all Within a heterogeneous population in which one group of bacterial cells, cannibal cells, expresses some skf and sdp genes, while the other group does not, the next sister group will be killed by these toxins because it has no immunity against them and will use the nutrients released to nourish other cells (cannibalism by sporulating bacteria. Science) (Cannibalism and fratricide: mechanisms, (Cannibalism enhances biofilm development) )(Production of the cannibalism toxin SDP)(Sporulating bacteria prefer predation)A study on cannibalism observed in Bacillus subtilis as these bacteria suffer from low concentration of nutrients and begin to form endospores, (Cannibalism and fratricide: mechanisms). in this way ba...... middle of paper ......nt progress in the sporulation of Bacillus subtilis. FEMS Microbiol Rev. 2012; 36(1): 131–148.• Subir Kumar Nandy SK, Bapat PM, Venkatesh KV. Sporulating bacteria prefer predation to cannibalism in mixed cultures .FEBS Letters .2007.581 :151–156• Lamsa A, Liu WT, Dorrestein PC, Pogliano K. The cannibalism toxin Bacillus subtilis SDP collapses the proton motive force and induces autolysis . Molecular microbiology. 2012. 84(3): 486–500_• Nandy SK, Prasad V, Venkatesh KV. Effect of temperature on the cannibalistic behavior of Bacillus subtilis.APPL. ENVIRONMENT. MICROBIOLOGY. 2008 ,74( 23): 7427–7430• Gonz´alez-Pastor JE, Hobbs EC & Losick R (2003) Cannibalism caused by sporulating bacteria. Science 301: 510–513.• Ellermeier CD, Hobbs EC, Gonz´alez-Pastor JE and Losick R (2006) A three-protein signaling pathway regulating immunity to abacterial cannibalism toxin. Cell 124: 549–559.