Burkitt lymphoma is a very aggressive form of B-cell non-Hodgkin lymphoma. The disease is related to the Epstein-Barr virus and was one of the first tumors to exhibit a chromosomal translocation. Burkitt lymphoma is the most common childhood cancer in which malaria is predominantly epidemic. About 10% of all malignant diseases in children under 15 years old. The disease is very common in those whose immune systems are not functionally efficient. With the help of intensive chemotherapy, children enjoy better health. On the other hand, children in third world countries are not as aggressive in treating Burkitt's lymphoma. The right prognosis helps doctors evaluate the early stages of Burkitt's lymphoma. Introduction and History A cancer that develops when white blood cells called lymphocytes grow abnormally is called lymphoma. Lymphocytes are found in the lymph nodes and target infections that collect in the lymph nodes. Lymph nodes are part of the lymphatic system that developed the immune system. Lymphatic tissues are also found in the lungs and intestines. These areas may require lymphocytes to fight infections or swallow food. Lymph nodes are found in many areas of the body: some of them can be felt if they are enlarged, others can only be seen on scans. Burkitt lymphoma is a form of non-Hodgkin lymphoma in which the cancer starts in immune cells called B cells. It is the fastest growing human cancer, Burkitt lymphoma is linked to a compromised immune system and, if left untreated, dies quickly; However, long-term survival can be achieved in more than half of people with Burkitt's lymphoma. At the end of World War II Burkitt sent military authorities to Africa. He was there and worked as a doctor... middle of paper... HIV – infected adults and children increase and HIV treatment becomes more effective and survival longer. Image tests can also detect tumors inside the body, such as CT scan, ultrasound, chest x-ray. Burkitt lymphoma can be treated with intensive chemotherapy. Treatment involves both intrathecal therapy and intravenous therapy. It takes several months to complete the treatment. The clinical characteristics of BL, over the years three trends have been identified in African BL that make this form of the disease more similar to the non-endemic form of BL with regards to the morbidity of BL: there has been a gradual decrease in BL newly diagnosed; there has been an increase in the age of patients with BL; There has been an increase in the incidence of abdominal cancers compared to head and neck cancers, especially among males compared to females.(9)